Potential adjuvants in drug formulation for Colon specific drug delivery system

Survi Barnawal, S Rajarajan, Beny Baby, K Ramesh, Sara Rai

Modern drug delivery techniques for the colon receive analysis because they provide vital therapeutic options to treat inflammatory bowel disease alongside other colon-based medical conditions. Drug product development succeeds because of understanding colon-specific factors including pH values along with microbial content. The research investigates three drug delivery techniques by explaining Prodrugs together with pH-sensitive substances and detection methods for colon bacteria to precisely release drugs. The available techniques enhance the absorption of poorly soluble drugs while minimizing systemic drug adverse responses. The paper identifies new ways to enhance patient outcomes yet the research community must first overcome multiple challenges related to developing secure pharmaceutical products. Better therapeutic treatments that focus on treating colonic disorders in patients require sustained research and innovation efforts.

Keywords –Potential Adjuvants, Colon Targeted Drug Delivery, Ulcerative Colitis, Microparticles, Inflammatory Bowel Disease (IBD).